Weight-loss drug user experiences: what users themselves report
Users’ own accounts, not research. The accounts are self-selected and prove neither that it works nor that it is safe.
We do not list users’ doses or where they got the medicine, and no figure here is a recommendation. The dose is for the doctor to decide.
Each substance below has its own page compiling public Reddit posts; an AI model read and classified every account following written instructions. People tend to post when something goes wrong, so the share does not tell how common harms are.
The weight-loss drug side-effects guide has its own section on the side effects users report. Its side-effect shares are higher than below because its posts were chosen for side-effect wording, while the posts of the summaries below are drawn from all posts about the medicine.
Semaglutide (Ozempic, Wegovy, Rybelsus)
People: 1345. 912 (68%) reported a benefit (most often: weight loss) and 711 (53%) some harm, most often: nausea (212, 16%), stomach pain or bloating (120, 9%) and vomiting (95, 7%).
Tirzepatide (Mounjaro)
People: 211. 165 (78%) reported a benefit (most often: weight loss) and 103 (49%) some harm, most often: nausea (37, 18%), burping (14, 7%), food aversion or eating too little (11, 5%), constipation (11, 5%) and diarrhoea (11, 5%).
Liraglutide (Saxenda, Victoza)
People: 188. 127 (68%) reported a benefit (most often: weight loss) and 123 (65%) some harm, most often: nausea (33, 18%), constipation (17, 9%) and stomach pain or bloating (16, 9%).
Retatrutide (no marketing authorisation: investigational drug)
People: 1182. 839 (71%) reported a benefit (most often: weight loss) and 611 (52%) some harm, most often: fatigue (98, 8%), food aversion or eating too little (78, 7%) and nausea (74, 6%). Retatrutide has no marketing authorisation, so the accounts are about products bought online whose contents are unknown.
Side effects users report: What users themselves report about side effects. What research shows: Weight-loss drugs (GLP-1): main page and which is which.
Content is general information about research, not medical advice. If you have symptoms, contact a healthcare professional.